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BDBM50173028 4-(4-(4-(benzyloxy)phenylamino)phthalazin-1-yl)benzamide::4-[4-(4-Benzyloxy-phenylamino)-phthalazin-1-yl]-benzamide::CHEMBL197357

SMILES: NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OCc3ccccc3)cc2)c2ccccc12

InChI Key: InChIKey=UPMAOTVCKCIDRZ-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173028   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50173028
PNG
(4-(4-(4-(benzyloxy)phenylamino)phthalazin-1-yl)ben...)
Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OCc3ccccc3)cc2)c2ccccc12
Show InChI InChI=1S/C28H22N4O2/c29-27(33)21-12-10-20(11-13-21)26-24-8-4-5-9-25(24)28(32-31-26)30-22-14-16-23(17-15-22)34-18-19-6-2-1-3-7-19/h1-17H,18H2,(H2,29,33)(H,30,32)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



ImClone Systems Inc

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF method


Bioorg Med Chem 17: 731-40 (2009)


Article DOI: 10.1016/j.bmc.2008.11.049
BindingDB Entry DOI: 10.7270/Q2W95929
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50173028
PNG
(4-(4-(4-(benzyloxy)phenylamino)phthalazin-1-yl)ben...)
Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OCc3ccccc3)cc2)c2ccccc12
Show InChI InChI=1S/C28H22N4O2/c29-27(33)21-12-10-20(11-13-21)26-24-8-4-5-9-25(24)28(32-31-26)30-22-14-16-23(17-15-22)34-18-19-6-2-1-3-7-19/h1-17H,18H2,(H2,29,33)(H,30,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



ImClone Systems

Curated by ChEMBL


Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide


Bioorg Med Chem Lett 15: 4696-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS
More data for this
Ligand-Target Pair