BDBM50173151 4-(3,5-Difluoro-3'-trifluoromethoxy-biphenyl-4-ylcarbamoyl)-2,5-dihydro-thiophene-3-carboxylic acid::CHEMBL194075

SMILES OC(=O)C1=C(CSC1)C(=O)Nc1c(F)cc(cc1F)-c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=RNGPMGBNTLQLBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173151   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50173151(4-(3,5-Difluoro-3'-trifluoromethoxy-biphenyl-4-ylc...)
Affinity DataIC50:  15nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed