BDBM50173259 1'-cyclooctylmethyl-1-ethyl-6-methoxyspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-2-one::CHEMBL199095

SMILES CCN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccc(OC)cc12

InChI Key InChIKey=SAENFLUGFXJZCR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173259   

TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173259(1'-cyclooctylmethyl-1-ethyl-6-methoxyspiro[2,3-dih...)
Affinity DataIC50: 1.46E+3nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173259(1'-cyclooctylmethyl-1-ethyl-6-methoxyspiro[2,3-dih...)
Affinity DataIC50: 2.75E+3nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173259(1'-cyclooctylmethyl-1-ethyl-6-methoxyspiro[2,3-dih...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human opioid receptor delta 1 expressed in HEK293 cells using [3H]DDPDE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed