BDBM50173665 3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1-carboxylic acid [4-(2-piperidin-1-yl-ethoxy)-phenyl]-amide::CHEMBL383372

SMILES CCC1=C(C(C(=O)Nc2ccc(OCCN3CCCCC3)cc2)c2cc(O)ccc12)c1ccc(O)cc1

InChI Key InChIKey=BDMZTIOJCDWABL-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173665   

TargetEstrogen receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50173665(3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1...)
Affinity DataEC50:  100nMAssay Description:Transcriptional activation of estrogen receptor alpha in U2OS cell using estrogen-regulated luciferase reporter gene plasmid upon incubation for 20-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50173665(3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1...)
Affinity DataKi:  147nMAssay Description:Antagonistic activity against estrogen receptor beta in presence of 0.1 nM estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50173665(3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1...)
Affinity DataKi:  184nMAssay Description:Antagonistic activity against estrogen receptor alpha in presence of 0.1 nM estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed