BDBM50173844 4-(3-chloro-4-fluorophenylamino)-6-(2-morpholino-1-phenylethylamino)-1,7-naphthyridine-3-carbonitrile::CHEMBL196919
SMILES Fc1ccc(Nc2c(cnc3cnc(NC(CN4CCOCC4)c4ccccc4)cc23)C#N)cc1Cl
InChI Key InChIKey=BOMGEFCTGNMKPY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50173844
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylationMore data for this Ligand-Target Pair