BDBM50173918 CHEMBL3809916
SMILES NC(=O)c1ccc2n([C@@H]3CCC[C@@H](C3)NC(=O)c3ccc(s3)C#N)c(nc2c1)-c1ccccn1
InChI Key InChIKey=FPWMCCRNEFWPIF-DLBZAZTESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50173918
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes using L-Serine and L-Leucine as substrate after overnight incubation by reverse-phase ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair