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BDBM50174050 CHEMBL365184::Diethyl-[2-(4-methyl-piperazin-1-yl)-2-(2-trifluoromethyl-phenyl)-ethyl]-amine

SMILES: CCN(CC)CC(N1CCN(C)CC1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=IXSIXHASDGLFGV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174050   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50174050
PNG
(CHEMBL365184 | Diethyl-[2-(4-methyl-piperazin-1-yl...)
Show SMILES CCN(CC)CC(N1CCN(C)CC1)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C18H28F3N3/c1-4-23(5-2)14-17(24-12-10-22(3)11-13-24)15-8-6-7-9-16(15)18(19,20)21/h6-9,17H,4-5,10-14H2,1-3H3
PDB

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PC cid
PC sid
UniChem
Article
PubMed
40n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptor


Bioorg Med Chem Lett 15: 4973-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.018
BindingDB Entry DOI: 10.7270/Q2HT2NWT
More data for this
Ligand-Target Pair