BDBM50174290 4-(5-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)bicyclo[2.2.2]octan-1-yl)-4-methyl-4H-1,2,4-triazol-3-yl)-3-methoxyphenol::CHEMBL373034

SMILES COc1cc(O)ccc1-c1nnc(n1C)C12CCC(CC1)(CC2)c1nc(no1)-c1ccc(F)cc1

InChI Key InChIKey=OWVVHBSDSJUALR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174290   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50174290(4-(5-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)b...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50174290(4-(5-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)b...)
Affinity DataIC50:  8.51nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50174290(4-(5-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)b...)
Affinity DataIC50:  8.60nMAssay Description:Inhibitory activity against human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed