BDBM50174452 (Z)-4-(7-Chloro-4-oxo-1,4-dihydro-quinolin-3-yl)-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL197118

SMILES OC(=O)C(=O)CC(=O)c1cnc2cc(Cl)ccc2c1O

InChI Key InChIKey=WAJYNFOETXZLFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174452   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50174452((Z)-4-(7-Chloro-4-oxo-1,4-dihydro-quinolin-3-yl)-2...)
Affinity DataIC50:  2.60E+4nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed