BDBM50174457 (Z)-6-[4-(4-Fluoro-benzoyl)-1-methyl-1H-pyrrol-2-yl]-2-hydroxy-4-oxo-hexa-2,5-dienoic acid::CHEMBL198879

SMILES Cn1cc(cc1C=CC(=O)CC(=O)C(O)=O)C(=O)c1ccc(F)cc1

InChI Key InChIKey=MWHNLHLQSBEVQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174457   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50174457((Z)-6-[4-(4-Fluoro-benzoyl)-1-methyl-1H-pyrrol-2-y...)
Affinity DataIC50:  1.60E+4nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed