BDBM50174558 7-hydroxy-2H-1-benzopyran-2-one::7-hydroxy-2H-chromen-2-one::CHEMBL51628::Coumarin derivative, 3a::beta-umbelliferone::hydrangin::skimmetin::umbelliferone

SMILES: c1cc2c(cc1O)OC(=O)C=C2

InChI Key: InChIKey=ORHBXUUXSCNDEV-UHFFFAOYSA-N

Data: 17 KI  18 IC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50174558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyceraldehyde-3-phosphate dehydrogenase (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.23E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+7	n/a	n/a	n/a	n/a	n/a	n/a
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Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sorbitol dehydrogenase (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 4 (Agaricus bisporus)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.36E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Seed linoleate 13S-lipoxygenase-1 (Soybean)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.67E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Genome polyprotein (HCV)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.66E+4	n/a	n/a	n/a	n/a	7.0	30
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Carbonic anhydrase 9 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		478	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		482	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		754	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Zn finger protein (Common tobacco)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		754	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		3.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		5.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		5.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		5.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50174558 (umbelliferone | CHEMBL51628 | skimmetin | Coumarin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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