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BDBM50174564 CHEMBL3808579

SMILES: Fc1ccc(\C=C2\S\C(NC2=O)=N/c2nc3cc(sc3s2)-c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=CMOPTOFHJYFAKJ-RQZCQDPDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174564   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
phosphatase Cdc25


(Homo sapiens (Human))
BDBM50174564
PNG
(CHEMBL3808579)
Show SMILES Fc1ccc(\C=C2\S\C(NC2=O)=N/c2nc3cc(sc3s2)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C21H11ClFN3OS3/c22-13-5-3-12(4-6-13)16-10-15-19(28-16)30-20(24-15)26-21-25-18(27)17(29-21)9-11-1-7-14(23)8-2-11/h1-10H,(H,24,25,26,27)/b17-9+
MMDB

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Article
PubMed
n/an/a 7.80E+3n/an/an/an/an/an/a



Universit£ de Lorraine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length GST-tagged CDC25A transfected in Escherichia coli BL21-DE3 using 3-O-methylfluorescein phosphate as subst...


Bioorg Med Chem 24: 2920-2928 (2016)


Article DOI: 10.1016/j.bmc.2016.04.063
BindingDB Entry DOI: 10.7270/Q22J6DS9
More data for this
Ligand-Target Pair