BDBM50174814 CHEMBL372551::N-[2-(3'-cyano-biphenyl-4-yl)-ethyl]-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-2-((S)-3-hydroxy-pyrrolidin-1-yl)-acetamide

SMILES O[C@H]1CCN(CC(=O)N(CCc2ccc(cc2)-c2cccc(c2)C#N)CC(=O)Nc2cc(Cl)cc(Cl)c2)C1

InChI Key InChIKey=BFVBGCXATBAVRX-MHZLTWQESA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174814   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50174814(CHEMBL372551 | N-[2-(3'-cyano-biphenyl-4-yl)-ethyl...)
Affinity DataKi:  3.70nMAssay Description:Antagonist activity against human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50174814(CHEMBL372551 | N-[2-(3'-cyano-biphenyl-4-yl)-ethyl...)
Affinity DataKi: >3.00E+3nMAssay Description:Antagonist activity against human MCH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed