BDBM50175341 (4S,7S,11aS)-7-benzamido-N4-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)-6-oxo-N2-phenyl-octahydro-1H-pyrazino[1,2-a]azocine-2,4(6H)-dicarboxamide::CHEMBL380780

SMILES OC1OC(=O)C[C@@H]1NC(=O)[C@@H]1CN(C[C@@H]2CCCC[C@H](NC(=O)c3ccccc3)C(=O)N12)C(=O)Nc1ccccc1

InChI Key InChIKey=IOVDCXCEGWOHSX-RUYZJNMWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175341   

TargetCaspase-8(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175341((4S,7S,11aS)-7-benzamido-N4-((3S)-2-hydroxy-5-oxo-...)
Affinity DataIC50:  601nMAssay Description:Inhibitory activity against Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175341((4S,7S,11aS)-7-benzamido-N4-((3S)-2-hydroxy-5-oxo-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175341((4S,7S,11aS)-7-benzamido-N4-((3S)-2-hydroxy-5-oxo-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against Caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed