BindingDB logo
myBDB logout

BDBM50175435 5-(2-carboxyphenyl)furan-2-carboxylic acid::CHEMBL197760

SMILES: OC(=O)c1ccc(o1)-c1ccccc1C(O)=O

InChI Key: InChIKey=WMUYPMCIAJSRIN-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175435   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175435
PNG
(5-(2-carboxyphenyl)furan-2-carboxylic acid | CHEMB...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C12H8O5/c13-11(14)8-4-2-1-3-7(8)9-5-6-10(17-9)12(15)16/h1-6H,(H,13,14)(H,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Fe(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175435
PNG
(5-(2-carboxyphenyl)furan-2-carboxylic acid | CHEMB...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C12H8O5/c13-11(14)8-4-2-1-3-7(8)9-5-6-10(17-9)12(15)16/h1-6H,(H,13,14)(H,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Co(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175435
PNG
(5-(2-carboxyphenyl)furan-2-carboxylic acid | CHEMB...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C12H8O5/c13-11(14)8-4-2-1-3-7(8)9-5-6-10(17-9)12(15)16/h1-6H,(H,13,14)(H,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.35E+4n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Mn(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175435
PNG
(5-(2-carboxyphenyl)furan-2-carboxylic acid | CHEMB...)
Show SMILES OC(=O)c1ccc(o1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C12H8O5/c13-11(14)8-4-2-1-3-7(8)9-5-6-10(17-9)12(15)16/h1-6H,(H,13,14)(H,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Ni(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.019
BindingDB Entry DOI: 10.7270/Q2HH6JNV
More data for this
Ligand-Target Pair