BDBM50175493 CHEMBL277931::N-[3-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccccc1
InChI Key InChIKey=ZVXCXEJBPDCMRL-UHFFFAOYSA-N
Data 18 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50175493
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of protein kinase A.More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against platelet-derived growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration against protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of protein kinase C delta.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of tyrosine kinase Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of tyrosine kinase(c-Src)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of serine/threonine kinase(PKC-delta)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibitory concentration against Src kinaseMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of serine/threonine kinase(PKC-alpha)More data for this Ligand-Target Pair