BDBM50175719 2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)pyrimidine::CHEMBL202238

SMILES C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1ncccn1)c1ccccc1

InChI Key InChIKey=XYHHNNJTSPIWFA-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175719   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50175719(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50175719(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  505nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50175719(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi: >4.65E+3nMAssay Description:Displacement of [3H]DAMGO from cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50175719(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataEC50:  14nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed