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BDBM50175825 3-bromo-4-ethoxy-N-(4-(5-methyl-1H-benzo[d]imidazol-2-yl)phenyl)benzamide::CHEMBL200701

SMILES: CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2[nH]1

InChI Key: InChIKey=PDRZSZWPFNBXDO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175825   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heparanase


(Homo sapiens (Human))
BDBM50175825
PNG
(3-bromo-4-ethoxy-N-(4-(5-methyl-1H-benzo[d]imidazo...)
Show SMILES CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2[nH]1
Show InChI InChI=1S/C23H20BrN3O2/c1-3-29-21-11-7-16(13-18(21)24)23(28)25-17-8-5-15(6-9-17)22-26-19-10-4-14(2)12-20(19)27-22/h4-13H,3H2,1-2H3,(H,25,28)(H,26,27)
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Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



ImClone Systems Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against heparanase from human platelets


Bioorg Med Chem Lett 16: 404-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.070
BindingDB Entry DOI: 10.7270/Q2FJ2G9R
More data for this
Ligand-Target Pair