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BDBM50175888 CHEMBL202750::benzyl (4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-11-[(tert-butyldimethylsilyl)oxy]-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate

SMILES: CC(C)(C)[Si](C)(C)O[C@@H]1C[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC=C2[C@@H]4CC(C)(C)CC[C@@]4(CC[C@@]32C)C(=O)OCc2ccccc2)C(C)(C)[C@H]1O

InChI Key: InChIKey=ZNZJRVRQJDIXTI-RDIZTWCZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175888   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50175888
PNG
(CHEMBL202750 | benzyl (4aS,6aS,6bR,8aR,10R,11R,12a...)
Show SMILES CC(C)(C)[Si](C)(C)O[C@@H]1C[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC=C2[C@@H]4CC(C)(C)CC[C@@]4(CC[C@@]32C)C(=O)OCc2ccccc2)C(C)(C)[C@H]1O
Show InChI InChI=1S/C43H68O4Si/c1-37(2,3)48(11,12)47-32-27-40(8)33(39(6,7)35(32)44)20-21-42(10)34(40)19-18-30-31-26-38(4,5)22-24-43(31,25-23-41(30,42)9)36(45)46-28-29-16-14-13-15-17-29/h13-18,31-35,44H,19-28H2,1-12H3/t31-,32+,33-,34+,35-,40-,41+,42+,43-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.71E+6n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibitory activity against rabbit muscle GPa


Bioorg Med Chem Lett 16: 722-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.014
BindingDB Entry DOI: 10.7270/Q22B8XMZ
More data for this
Ligand-Target Pair