BDBM50175901 8-((1S,2S)-2-phenyl-cyclohexyl)-1-propyl-1,3,8-triaza-spiro[4.5]decan-4-one::8-((cis, rac)-2-phenyl-cyclohexyl)-1-propyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL372402
SMILES CCCN1CNC(=O)C11CCN(CC1)[C@H]1CCCC[C@H]1c1ccccc1
InChI Key InChIKey=LJMDGQMIYHIQTC-PMACEKPBSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50175901
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Displacement of [3H]glycine from human GlyT1 by radiometric assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT2 cDNAMore data for this Ligand-Target Pair