BDBM50175910 1-(4-fluoro-phenyl)-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL370111

SMILES Fc1ccc(cc1)N1CNC(=O)C11CCN(CC1)[C@H]1CCCC[C@H]1c1ccccc1

InChI Key InChIKey=HIOFFNLYGYBMSJ-GOTSBHOMSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175910   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175910(1-(4-fluoro-phenyl)-8-((1S,2S)-2-phenyl-cyclohexyl...)
Affinity DataEC50:  2.30E+4nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT2 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175910(1-(4-fluoro-phenyl)-8-((1S,2S)-2-phenyl-cyclohexyl...)
Affinity DataEC50:  24nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed