BDBM50176127 (Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]-2-hydroxy-4-oxo-but-2-enoic acid ethyl ester::CHEMBL365604

SMILES CCOC(=O)C(=O)CC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key InChIKey=LGELEWDEOBTUOD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176127   

TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176127((Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]...)
Affinity DataIC50: 70nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176127((Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]...)
Affinity DataIC50: 390nMAssay Description:In vitro concentration required to inhibit the overall HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176127((Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]...)
Affinity DataIC50: 1.15E+4nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase 3' strand transferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed