BDBM50176995 CHEMBL3814018

SMILES OC(=O)CCCOc1cccc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)C(O)=O)c(=O)[nH]c2=O)c1

InChI Key InChIKey=TWNCXCUPSVACQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176995   

TargetCollagenase 3(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50176995(CHEMBL3814018)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant MMP13 (85 to 255 residues) expressed in Escherichia coli using 5-FAM/QXLTM as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Zhaw Zurich University Of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50176995(CHEMBL3814018)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50176995(CHEMBL3814018)
Affinity DataIC50:  6nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed