BDBM50177051 3-azepan-1-yl-9-(dimethylnitroryl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one::9-(N,N-dimethyl-N-oxyamino)-3-(N-hexamethyleneiminyl)-3H-5-thia-1,3,6-triaza-fluoren-4-one::CHEMBL386408

SMILES C[N+](C)([O-])c1ccnc2sc3c(ncn(N4CCCCCC4)c3=O)c12

InChI Key InChIKey=AKXCOQICNDOOTF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177051   

TargetMetabotropic glutamate receptor 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177051(9-(N,N-dimethyl-N-oxyamino)-3-(N-hexamethyleneimin...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at rat mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177051(9-(N,N-dimethyl-N-oxyamino)-3-(N-hexamethyleneimin...)
Affinity DataIC50: 167nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177051(9-(N,N-dimethyl-N-oxyamino)-3-(N-hexamethyleneimin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177051(9-(N,N-dimethyl-N-oxyamino)-3-(N-hexamethyleneimin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed