BDBM50177238 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-pentanoyl-piperazine-2-carboxylic acid (1H-imidazol-2-ylmethyl)-amide::CHEMBL383236

SMILES CCCCC(=O)N1CCN(CC1C(=O)NCc1ncc[nH]1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12

InChI Key InChIKey=QZPVPNVPXFQKML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177238   

LigandPNGBDBM50177238(4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against farnesyltransferase quantified by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50177238(4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Ha-Ras processing in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed