BDBM50177607 (R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-ylamino)butan-1-ol::CHEMBL274737

SMILES CC[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(N)sc12

InChI Key InChIKey=NPKHWEBWIFDKHH-LLVKDONJSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177607   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50177607((R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimi...)
Affinity DataKi:  160nMAssay Description:Displacement of [125I]-IL8 from human CXCR2 transfected in HEK293 cells after 4 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCX3C chemokine receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50177607((R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimi...)
Affinity DataKi:  770nMAssay Description:Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50177607((R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimi...)
Affinity DataIC50:  120nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed