BDBM50177691 3-(trans-4,5-dimethyl-1,2(alpha)-diphenethylpiperidin-4-yl)phenol::CHEMBL201434

SMILES C[C@H]1CN(CCc2ccccc2)[C@H](CCc2ccccc2)C[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=QXGODTNSOZTPPI-TZIIFLTASA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177691   

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177691(3-(trans-4,5-dimethyl-1,2(alpha)-diphenethylpiperi...)
Affinity DataKi:  160nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177691(3-(trans-4,5-dimethyl-1,2(alpha)-diphenethylpiperi...)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177691(3-(trans-4,5-dimethyl-1,2(alpha)-diphenethylpiperi...)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177691(3-(trans-4,5-dimethyl-1,2(alpha)-diphenethylpiperi...)
Affinity DataIC50:  210nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed