BDBM50177810 2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino}-5-[(3-phenylprop-2-yn-1-yl)oxy]benzo-1,4-quinone::CHEMBL372606

SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(OCC#Cc4ccccc4)=CC3=O)c2cc1OC

InChI Key InChIKey=TWUSXZPLMMKGAY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177810   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177810(2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177810(2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177810(2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50:  17nMAssay Description:Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATP and in presence of 5% mouse plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed