BDBM50177851 2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino}-5-pyrrolidin-1-ylbenzo-1,4-quinone::CHEMBL200316

SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(=CC3=O)N3CCCC3)c2cc1OC

InChI Key InChIKey=BKKWOMCXAMAYFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177851   

TargetVascular endothelial growth factor receptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177851(2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50: 372nMAssay Description:Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177851(2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATP and in presence of 5% mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177851(2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATP and in presence of 100 uM glutathioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed