BDBM50178287 CHEMBL3814785

SMILES CCc1cc(nc(N)n1)-c1c[nH]c2ncc(cc12)-c1cnn(C)c1

InChI Key InChIKey=HNXOSEYAHXEERE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178287   

LigandPNGBDBM50178287(CHEMBL3814785)
Affinity DataIC50: 85nMAssay Description:Inhibition of human His6-tagged PDK1 using biotinylated PDKtide as substrate after 60 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
LigandPNGBDBM50178287(CHEMBL3814785)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
LigandPNGBDBM50178287(CHEMBL3814785)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3K delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
LigandPNGBDBM50178287(CHEMBL3814785)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PDK1 in human PC3 cells assessed as reduction in AKT Thr308 phosphorylation after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed