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BDBM50178734 CHEMBL425205::N-(3-(5-chlorobenzo[d]oxazol-2-yl)-4-hydroxyphenyl)nicotinamide

SMILES: Oc1ccc(NC(=O)c2cccnc2)cc1-c1nc2cc(Cl)ccc2o1

InChI Key: InChIKey=WIHRFNNSKIZHAF-UHFFFAOYSA-N

Data: 2 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178734   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50178734
PNG
(CHEMBL425205 | N-(3-(5-chlorobenzo[d]oxazol-2-yl)-...)
Show SMILES Oc1ccc(NC(=O)c2cccnc2)cc1-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C19H12ClN3O3/c20-12-3-6-17-15(8-12)23-19(26-17)14-9-13(4-5-16(14)24)22-18(25)11-2-1-7-21-10-11/h1-10,24H,(H,22,25)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 6.10E+4n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Inhibition of 3'-processing catalytic activity HIV1 integrase


J Med Chem 48: 8009-15 (2005)


Article DOI: 10.1021/jm050837a
BindingDB Entry DOI: 10.7270/Q2GX4B4Q
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50178734
PNG
(CHEMBL425205 | N-(3-(5-chlorobenzo[d]oxazol-2-yl)-...)
Show SMILES Oc1ccc(NC(=O)c2cccnc2)cc1-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C19H12ClN3O3/c20-12-3-6-17-15(8-12)23-19(26-17)14-9-13(4-5-16(14)24)22-18(25)11-2-1-7-21-10-11/h1-10,24H,(H,22,25)
PDB
MMDB

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Inhibition of strand transfer catalytic activity HIV1 integrase


J Med Chem 48: 8009-15 (2005)


Article DOI: 10.1021/jm050837a
BindingDB Entry DOI: 10.7270/Q2GX4B4Q
More data for this
Ligand-Target Pair