BDBM50178769 (+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL420311

SMILES: NC(=O)C1CCCc2c1[nH]c1ccc(Cl)cc21

InChI Key: InChIKey=FUZYTVDVLBBXDL-UHFFFAOYSA-N

Data: 1 KI  53 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 54 hits for monomerid = 50178769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50178769 (6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair