BDBM50179207 3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine::CHEMBL120077::JNJ-10198409

SMILES: COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC

InChI Key: InChIKey=ZDNURMVOKAERHZ-UHFFFAOYSA-N

Data: 34 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 50179207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin receptor (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Casein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Human)	BDBM50179207 (JNJ-10198409 | 3-fluoro-N-(6,7-dimethoxy-2,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair