BDBM50179487 3-(5-(benzo[d][1,3]dioxol-5-ylamino)-1,3,4-oxadiazol-2-yl)-N-(pyridin-3-ylmethyl)pyridin-2-amine::CHEMBL382359

SMILES C(Nc1ncccc1-c1nnc(Nc2ccc3OCOc3c2)o1)c1cccnc1

InChI Key InChIKey=DWTQAMVPEXBCOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179487   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179487(3-(5-(benzo[d][1,3]dioxol-5-ylamino)-1,3,4-oxadiaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR-2 kinase assessed as phosphorylated level of pGAT-biotin peptide preincubated for 5 to 10 mins before addtion of substrate measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179487(3-(5-(benzo[d][1,3]dioxol-5-ylamino)-1,3,4-oxadiaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 expressed HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed