BDBM50179522 CHEMBL3814289

SMILES COc1ccc2c(c1)oc(=O)n(Cc1cccc(NS(=O)(=O)NCCC#N)c1F)c2=O

InChI Key InChIKey=AYAZLPMZEOHROO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179522   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50179522(CHEMBL3814289)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human BRAF/MEK1/RAF1 Y340D/Y341D double mutant measured after 2 hrs in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed