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BDBM50179535 CHEMBL205923::N-(2-(4-methoxyphenylamino)ethyl)-4-methyl-2-phenoxypentanamide

SMILES: COc1ccc(NCCNC(=O)C(CC(C)C)Oc2ccccc2)cc1

InChI Key: InChIKey=FUZCWYPPEATDPO-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179535   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (Human))
BDBM50179535
PNG
(CHEMBL205923 | N-(2-(4-methoxyphenylamino)ethyl)-4...)
Show SMILES COc1ccc(NCCNC(=O)C(CC(C)C)Oc2ccccc2)cc1
Show InChI InChI=1/C21H28N2O3/c1-16(2)15-20(26-19-7-5-4-6-8-19)21(24)23-14-13-22-17-9-11-18(25-3)12-10-17/h4-12,16,20,22H,13-15H2,1-3H3,(H,23,24)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human Cathepsin K


Bioorg Med Chem Lett 16: 1502-5 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.053
BindingDB Entry DOI: 10.7270/Q2T154FS
More data for this
Ligand-Target Pair