BDBM50180124 3,5-dimethyl-4-hydroxy-5-(2-methoxybenzyl)-5H-thiophen-2-one::CHEMBL199810

SMILES COc1ccccc1CC1(C)SC(=O)C(C)C1=O

InChI Key InChIKey=KRLPCVKPHNHATA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50180124   

Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Escherichia coli (strain K12))
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50180124(3,5-dimethyl-4-hydroxy-5-(2-methoxybenzyl)-5H-thio...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against FabB from Escherichia coli ANSIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50180124(3,5-dimethyl-4-hydroxy-5-(2-methoxybenzyl)-5H-thio...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against FabH from Mycobacterium tuberculosis H37RvMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 2(Mycobacterium tuberculosis)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50180124(3,5-dimethyl-4-hydroxy-5-(2-methoxybenzyl)-5H-thio...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against KasB from Mycobacterium tuberculosis H37RvMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50180124(3,5-dimethyl-4-hydroxy-5-(2-methoxybenzyl)-5H-thio...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against FabH from Escherichia coli ANSIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50180124(3,5-dimethyl-4-hydroxy-5-(2-methoxybenzyl)-5H-thio...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against KasA from Mycobacterium tuberculosis H37RvMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed