BDBM50180346 2-(Phenyl-N-methylamino)-6-(3-acetamidophenyl)pyrazine::CHEMBL199805

SMILES CN(Nc1cncc(n1)-c1cccc(NC(C)=O)c1)c1ccccc1

InChI Key InChIKey=DHWSDQAWLZEOQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180346   

TargetSerine/threonine-protein kinase B-raf(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180346(2-(Phenyl-N-methylamino)-6-(3-acetamidophenyl)pyra...)
Affinity DataIC50: 4.96E+4nMAssay Description:Growth inhibition in human melanoma cells WM266.4 expressing mutant B-RAF with SRBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180346(2-(Phenyl-N-methylamino)-6-(3-acetamidophenyl)pyra...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against human B-RAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed