BDBM50180351 2-(2,4-Dimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine::CHEMBL201272

SMILES COc1ccc(Nc2cncc(n2)-c2cccc(NC(C)=O)c2)c(OC)c1

InChI Key InChIKey=MVRQJAIGNAEYLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180351   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180351(2-(2,4-Dimethoxyphenylamino)-6-(3-acetamidophenyl)...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against human B-RAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180351(2-(2,4-Dimethoxyphenylamino)-6-(3-acetamidophenyl)...)
Affinity DataIC50:  8.80E+3nMAssay Description:Growth inhibition in human melanoma cells WM266.4 expressing mutant B-RAF with SRBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed