BDBM50180652 CHEMBL3819527
SMILES CN1CCN(CC(=O)N2N=C3C(CCC\C3=C/c3ccccc3)C2c2ccccc2)CC1
InChI Key InChIKey=GEMFAWUXUVGGTE-FCDQGJHFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50180652
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataKd: 3.90E+3nMAssay Description:Binding affinity to wild-type His6-tagged human 15-LOX expressed in Escherichia coli Rosetta DE3 by SPR assayMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mPGES-1 (unknown origin) assessed as reduction in conversion of PGH2 to PGE2 by EIA methodMore data for this Ligand-Target Pair