BDBM50180661 Norfluoxetine

SMILES NCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=WIQRCHMSJFFONW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180661   

TargetPotassium channel subfamily K member 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180661BDBM50180661(Norfluoxetine)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human TREK1 channel expressed in HEK293 cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPotassium channel subfamily K member 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180661BDBM50180661(Norfluoxetine)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of of human TREK1 expressed in tsA201 cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed