BDBM50180708 7-tert-butyl-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one::CHEMBL199393

SMILES CC(C)(C)c1nc2[nH]c(=S)[nH]c(=O)c2cc1-c1ccccc1

InChI Key InChIKey=ZJASONAERXCSAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50180708   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180708(7-tert-butyl-6-phenyl-2-thioxo-2,3-dihydro-1H-pyri...)
Affinity DataIC50: 25nMAssay Description:Inhibition of low pH activation of rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180708(7-tert-butyl-6-phenyl-2-thioxo-2,3-dihydro-1H-pyri...)
Affinity DataIC50: 49nMAssay Description:Inhibition of low pH activation of human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180708(7-tert-butyl-6-phenyl-2-thioxo-2,3-dihydro-1H-pyri...)
Affinity DataIC50: 90nMAssay Description:Inhibition of calcium influx evoked by capsaicin in rat TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180708(7-tert-butyl-6-phenyl-2-thioxo-2,3-dihydro-1H-pyri...)
Affinity DataIC50: 100nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed