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BDBM50180768 3,6-[4-(pyrrolidin-1-yl)butanamido]-9-[4'-(N,N-dimethylamino)anilino]acridine::CHEMBL201697

SMILES: CN(C)c1ccc(Nc2c3ccc(NC(=O)CCCN4CCCC4)cc3nc3cc(NC(=O)CCCN4CCCC4)ccc23)cc1

InChI Key: InChIKey=XWLUQMHOSNAPOE-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180768   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50180768
PNG
(3,6-[4-(pyrrolidin-1-yl)butanamido]-9-[4'-(N,N-dim...)
Show SMILES CN(C)c1ccc(Nc2c3ccc(NC(=O)CCCN4CCCC4)cc3nc3cc(NC(=O)CCCN4CCCC4)ccc23)cc1
Show InChI InChI=1S/C37H47N7O2/c1-42(2)30-15-11-27(12-16-30)40-37-31-17-13-28(38-35(45)9-7-23-43-19-3-4-20-43)25-33(31)41-34-26-29(14-18-32(34)37)39-36(46)10-8-24-44-21-5-6-22-44/h11-18,25-26H,3-10,19-24H2,1-2H3,(H,38,45)(H,39,46)(H,40,41)
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PC cid
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Similars

Article
PubMed
n/an/an/an/a 99n/an/an/an/a



University of London

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity from human A2780 cells


J Med Chem 49: 582-99 (2006)


Article DOI: 10.1021/jm050555a
BindingDB Entry DOI: 10.7270/Q2CN73GR
More data for this
Ligand-Target Pair