BDBM50180925 11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(18),3(8),4,6,14,16-hexaene::7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::CHEMBL201525

SMILES CN1CCc2ccccc2Cc2ccccc2CC1

InChI Key InChIKey=BXOLXXSMCLYDNG-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50180925   

TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  3.09nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  3.47nMAssay Description:Displacement of [3H]SCH23390 from human cloned dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  8.47nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  11.2nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  11.2nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  40.4nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  47.5nMAssay Description:Inhibition of binding to human D3 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  52.5nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  56.5nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  56.5nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  58.9nMAssay Description:Displacement of [3H]SCH23390 from human cloned dopamine D2L receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  134nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed