BDBM50181532 CHEMBL201307::N-(3-fluorophenyl)-2-(2-(7-(3-(4-(hydroxymethyl)piperidin-1-yl)propoxy)-6-methoxyquinazolin-4-ylamino)thiazol-5-yl)acetamide::N-(3-fluorophenyl)-2-{2-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}acetamide::N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidin-1-yl)propoxy)-6-methoxyquinazolin-4-ylamino)thiazol-5-yl)acetamide

SMILES: COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(F)c4)s3)ncnc2cc1OCCCN1CCC(CO)CC1

InChI Key: InChIKey=QNJAKUMXJFWQOG-UHFFFAOYSA-N

Data: 18 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50181532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1/2/3/4 (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50181532 (N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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