BDBM50181669 5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid [4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-amide::CHEMBL370800

SMILES: CN1CCN(Cc2ccc(NC(=O)c3cc(c[nH]c3=O)-c3ccc4OCOc4c3)cc2)CC1

InChI Key: InChIKey=OIGYTQZVSAHUAD-UHFFFAOYSA-N

Data: 2 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50181669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor/Nucleophosmin (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor/Nucleophosmin (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ALK tyrosine kinase receptor (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	GoogleScholar	UniChem		5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair