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BDBM50182008 CHEMBL203675::N-(5-bromo-2-methylphenyl)-7-(pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

SMILES: Cc1ccc(Br)cc1Nc1ncc2ccn(-c3ccccn3)c2n1

InChI Key: InChIKey=ISGWLGARRZAQJJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182008   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))
BDBM50182008
PNG
(CHEMBL203675 | N-(5-bromo-2-methylphenyl)-7-(pyrid...)
Show SMILES Cc1ccc(Br)cc1Nc1ncc2ccn(-c3ccccn3)c2n1
Show InChI InChI=1S/C18H14BrN5/c1-12-5-6-14(19)10-15(12)22-18-21-11-13-7-9-24(17(13)23-18)16-4-2-3-8-20-16/h2-11H,1H3,(H,21,22,23)
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK


Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair