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BDBM50182022 CHEMBL3818467

SMILES: COc1cccc(CSc2nc3c(nc(N)[nH]c3=O)[nH]2)c1

InChI Key: InChIKey=UZICLMSCCMEGFA-UHFFFAOYSA-N

Data: 2 Kd

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182022   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase


(Escherichia coli (strain K12))
BDBM50182022
PNG
(CHEMBL3818467)
Show SMILES COc1cccc(CSc2nc3c(nc(N)[nH]c3=O)[nH]2)c1
Show InChI InChI=1S/C13H13N5O2S/c1-20-8-4-2-3-7(5-8)6-21-13-15-9-10(17-13)16-12(14)18-11(9)19/h2-5H,6H2,1H3,(H4,14,15,16,17,18,19)
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 1.80E+3n/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Binding affinity to biotinylated Escherichia coli HPPK expressed in Escherichia coli BL21 (DE3) in presence of 1 mM ATP by SPR assay


Citation and Details
More data for this
Ligand-Target Pair
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase


(Staphylococcus aureus)
BDBM50182022
PNG
(CHEMBL3818467)
Show SMILES COc1cccc(CSc2nc3c(nc(N)[nH]c3=O)[nH]2)c1
Show InChI InChI=1S/C13H13N5O2S/c1-20-8-4-2-3-7(5-8)6-21-13-15-9-10(17-13)16-12(14)18-11(9)19/h2-5H,6H2,1H3,(H4,14,15,16,17,18,19)
PDB

KEGG

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 650n/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Binding affinity to biotinylated Staphylococcus aureus HPPK in presence of 1 mM ATP by SPR assay


Citation and Details
More data for this
Ligand-Target Pair