BDBM50182518 CHEMBL3819436::US9512121, 19

SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5NC(=O)COc5c4c3)n2c1

InChI Key InChIKey=ZTJLCACQNPNSHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182518   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182518(CHEMBL3819436 | US9512121, 19)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of c-Met (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182518(CHEMBL3819436 | US9512121, 19)
Affinity DataIC50:  7.90nMT: 2°CAssay Description:Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...More data for this Ligand-Target Pair
In DepthDetails US Patent