BDBM50182525 4-(2,2-diphenyl-1-ethyl)-5-(4-piperidyl)isothiazol-3-ol::CHEMBL204189

SMILES O=c1[nH]sc(C2CCNCC2)c1CC(c1ccccc1)c1ccccc1

InChI Key InChIKey=KVMKDFFHDINSSZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182525   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50182525(4-(2,2-diphenyl-1-ethyl)-5-(4-piperidyl)isothiazol...)
Affinity DataKi:  720nMAssay Description:Binding affinity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed